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Compared with a lower dose, intensive treatment with atorvastatin in patients with stable coronary disease significantly reduces hospitalizations for HF.
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n this study of physicians working in French adult ICUs, evidence of burnout was present in nearly half. Burnout was more likely in female physicians, in those who were not married, and among those who reported strained relationships with colleagues and staff nurses.
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A combination of topical and systemic therapies was associated with successful MRSA decolonization.
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Delirium occurred in about one-third of patients in this study of a mixed medical-surgical ICU population. It was more frequent in more seriously ill patients, and also in those with hypertension, alcoholism, and the effects of sedative and analgesic drugs.
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Vancomycin was inferior to cefazolin in the treatment of MSSA bacteremia in chronic hemodialysis patients in a retrospective study.
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Aspirin can be life saving in patients with acute coronary events, but its use in patients with cancer, particularly in those with thrombocytopenia, is often avoided, presumably for fear of hemorrhagic complications.
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Status epilepticus, in the setting of cancer, is treatable and does not appear to increase mortality above the risk of the underlying disease.
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Because of adverse effects, special care should be used when prescribing the atypical antipsychotic drugs for patients with dementia.
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Salvage therapy of invasive aspergillosis with posaconazole was associated with a 42% response rate, compared to only 26% in an external control group.
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Using the metyrapone test as a gold standard, the authors confirmed that a resting serum cortisol level < 10 micrograms/dL, or an increase of < 9 micrograms/dL after cosyntropin stimulation, accurately diagnoses adrenal insufficiency in ICU patients with severe sepsis or septic shock.
