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While a number of antiretroviral agents have been implicated in contributing to both insulin resistance and lipid abnormalities, HIV also directly causes metabolic disturbances.
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A double-blind, randomized, controlled trial conducted by the International Neonatal Immunotherapy Study (INIS) compared adjunctive therapy of human nonspecific polyvalent IgG intravenous immune globulin to placebo in the treatment of newborn infants with suspected or proven sepsis who were also receiving antibiotic therapy.
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Baseline production of PSMa subtypes was examined in 50 PVL-positive methicillin-susceptible Staphylococcus aureus (MSSA) and MRSA clinical isolates using liquid chromatography-tandem mass spectrometry (LC-MS-MS), and these results were compared to a control strain, LAC (USA300). MICs were determined using a broth macrodilution method.
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Outpatients with a diagnosis of either dentoalveolar or periodontal abscess or a diagnosis of gingival inflammatory infiltrates were randomized to receive either moxifloxacin 400 mg daily or clindamycin 300 mg QID, both for 5 days, in a prospective, randomized, placebo-controlled, double-dummy clinical trial design.
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A total of 783 children 6-24 months of age were followed for an entire respiratory season by four experienced otoscopists using pneumatic otoscopy of one ear, randomly selected for each child.
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The continuing state and federal mandates requiring hospitals to report healthcare associated infections threatens to outstrip their original justification, raising questions about whether the labor-intensive efforts will result in true reductions of HAIs, warned Patricia Stone, PhD, FAAN, professor of nursing and director of the Center for Health Policy at Columbia University in New York City.
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The Centers for Medicare and Medicaid Services controversial 2008 policy to cut reimbursement for selected health care associated infections (HAIs) has led to some positive prevention measures while fulfilling some predicted unintended consequences, according to an unpublished national survey of infection preventionists.
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As the U.S. Occupational Safety and Health Administration moves deliberatively toward an infectious diseases standard, two paradigms could spell very different fates for a proposed rule.
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The U.S. public health system is trying to catch up with the explosion of infections with multidrug resistant gram negative rods (MDR-GNR) by standardizing surveillance definitions and changing laboratory breakpoints.
