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The different drug formulations of menopausal hormone therapy (HT) may determine the risk of venous thromboembolism (VTE), according to a new study. It is known that combined estrogen-progesterone therapy has a higher risk of VTE than estrogen-only therapy, and oral therapy has a higher risk than transdermal therapy.
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A remarkably large number of presentations at IDWeek held in San Diego October 17-21, 2012, dealt directly with issues of antimicrobial stewardship. These included aspects such as documenting the frequency of inappropriate antibiotic use in various settings together with descriptions of successful interventions.
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There are very little data on antibiotic stewardship in LTCF. This work (Jump et al.) came from a Geriatric Research Education and Clinical Center (GRECC) demonstration project at the Cleveland VA Medical Center. The LID was a LTCF Infectious Disease team that provided on site consultations.
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In the first report (Newland et al), a quasi-experimental study with a control group (also known as a nonrandomized, postintervention design) was performed from 20042010 to determine the impact of an antimicrobial stewardship program (ASP) implemented in March, 2008 in a tertiary care children's hospital that was based on prospective-audit-with-feedback.
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One of the unintended consequences of the Centers for Medicare and Medicaid Services (CMS) performance measures for CAP was that clinicians often started antibiotics too quickly in patients without infection. Subsequently, the requirement that antibiotics be initiated within 6 hours of patient presentation was retired as of January 1, 2012.
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Dealing with cytomegalovirus (CMV) can be vexing for everybody involved, but a recent paper may help with the management and counseling of patients infected with this virus at different times before and during pregnancy.
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Hong Kong investigators conducted 2 separate community studies using careful face-to-face instructions to potentially influenza infected patients. Sterile nasal swabs were rotated around the anterior nares.
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In this issue: Statins and diabetes risk; new treatment guideline for diabetes; new pertussis vaccine recommendation; antibiotics and rhinosinusitis; fluoroquinolones and cystitis; and FDA actions.
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Infection is the second leading cause of death in hemodialysis patients, with mortality rates ranging from 12-36% in this vulnerable population.
