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From November 2003 to November 2005, 254 cases of childhood diarrhea and 452 age- and geographically-matched (by zip code) controls were enrolled in a case-control study of the etiology of acute diarrhea among children 10-49 months of age presenting to a pediatric emergency department.
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Two men (one age 57 with no prior significant illnesses and one age 67 with type 2 diabetes) from northwestern Missouri presented separately to a hospital with illnesses characterized by fever, fatigue, diarrhea, thrombocytopenia and leukopenia. Hepatic transaminase levels subsequently became elevated in both patients, peaking between 8 and 10 days.
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Three HIV-infected patients with refractory, corticosteroid-dependent and life-threatening IRIS were presented.
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In this issue: Side effects of statins; effects of cannabis use; antihypertensives and lip cancer; and FDA actions.
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Clostridium difficile infection (CDI) is a major complication associated with antibiotic usage, and its incidence continues to increase. Management of CDI remains challenging despite new therapies and many patients suffer from recurrences. Interventions to limit acquisition of the disease are therefore urgently needed.
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Travel to the Middle East may have gotten less popular recently, but for those planning to travel for the annual pilgrimage to Makkah (Mecca) October 24-29, 2012, The National Travel Health Network has issued updated guidelines, as follows:
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Uwanyiligira et al retrospectively analyzed charts of all patients seen at the Travel Clinic of the University Hospital in Lausanne, Switzerland, for rabies post-exposure prophylaxis (PEP) between January 2005 and August 2011.
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Prior to 2012, only 2 cases of hantavirus infection had been identified in visitors to California's Yosemite National Park one in 2000 and another in 2010. Both infections were acquired in the Tuolomne Meadows area, miles distant from the iconic Yosemite Valley.
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Effective antimicrobial stewardship is of particular importance in the developing world. In many developing countries, inappropriate antimicrobial use has led to widespread drug resistance among not only bacterial isolates, but also among parasites and other infectious agents.
