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  • Lessons from the 2009 Pandemic Flu Experience

    Jain and colleagues at the U.S. CDC evaluated the characteristics of 195 hospitalized patients with laboratory-confirmed influenza influenza A pdm09 (pH1N1) infection who had pneumonia, comparing them to hospitalized flu patients without pneumonia.
  • Updates by Carol A. Kemper, MD, FACP

    HIV Risk Triplesin Women with an STD Mlisana K, et al. Symptomatic vaginal discharge is a poor predictor of sexually transmitted infections and genital tract inflammation in high-risk women in South Africa. J Infect Dis 2012;206:6-14. Classical sexually transmitted diseases drive the spread of HIV-1: Back to the future. J Infect Dis 2012;206:1-2.
  • Pharmacology Update: Does Azithromycin Cause Cardiovascular Death?

    In this issue: Azithromycin and cardiac risk; warfarin and heart failure; aspirin and VTE; effectiveness of long-acting contraceptives; and FDA actions.
  • Diagnosis and Treatment of Influenza: Rapid Tests and Antiviral Options

    Recent ACIP recommendations for the management of influenza virus infections include: "1) early antiviral treatment of suspected or confirmed influenza among persons with severe influenza (e.g., those who have severe, complicated, or progressive illness or who require hospitalization); 2) early antiviral treatment of suspected or confirmed influenza among persons at higher risk for influenza complications; and 3) either oseltamivir or zanamivir for persons with influenza caused by 2009 H1N1 virus, influenza A (H3N2) virus, or influenza B virus or when the influenza virus type or influenza A virus subtype is unknown; 4) oseltamivir may be used for treatment or chemoprophylaxis of influenza among infants aged <1 year when indicated; 5) local influenza testing and influenza surveillance data, when available, to help guide treatment decisions; and 6) consideration of antiviral treatment for outpatients with confirmed or suspected influenza who do not have known risk factors for severe illness, if treatment can be initiated within 48 hours of illness onset."
  • ID groups urge CMS to mandate antimicrobial stewardship programs

    Infectious disease societies frustrated at watching antimicrobial resistance increase for decades are taking the unusual step of asking for federal regulation and oversight of clinical practice, imploring the Centers for Medicare & Medicaid Services (CMS) to require hospitals to implement antimicrobial stewardship programs.
  • Post-script review, feedback curtails antibiotic use

    A new multicenter study shows that antimicrobial stewardship expressed as a post-prescription review and feedback intervention can decrease antimicrobial use, especially when it's part of an established antimicrobial program.
  • Does the patient need IV drugs at discharge?

    Investigators evaluating more than 240 patients over a three-month period found that infectious diseases (ID) physicians correctly identified patients who did not need to be discharged on community-based parenteral anti-infective therapy (CoPAT).
  • Norovirus outbreaks trigger unit closures

    Norovirus is the organism most likely to trigger a shutdown of units in your hospital. And according to a recent survey of infection preventionists, it is responsible for more outbreaks than some deadlier organisms, such as Clostridium difficile and Staphylococcus aureus.
  • The Joint Commission Update for Infection Control: HAIs a high priority: Joint Commission gives infection prevention its own web portal

    In yet another sign that infection control is becoming a national priority across a wide range of accreditors, regulators and state and federal agencies, the Joint Commission has created a new web portal to combine its full array of initiatives to prevent health care associated infections (HAIs).
  • Changing the antibiotic mindset of docs, patients

    In addition to calling for federal regulation requiring antimicrobial stewardship, a position paper by leading infectious disease groups recommended several other measures to preserve remaining antibiotic efficacy.