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The excess risk of Achilles tendon disorders attributable to fluoroquinolone use was estimated to be 3.2 cases per 1000 patient-years, with most of that increase accounted for by patients 60 years of age and older who concomitantly receive corticosteroids.
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The CDC has published a new set of recommendations aimed at preventing health care-associated infections by optimizing hand hygiene in health care personnel. The following is a summary of some of those recommendations, selected because of their strength and/or novelty.
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Passage through the human gastrointestinal tract enhances the infectiousness of Vibrio cholerae.
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In this feature, brief items, primarily gleaned from abstracts or articles in journals and other resources not commonly perused by most US
infectious disease physicians, will be presented, usually without comment.
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High-Dose Rofecoxib Confirmed Prothrombotic, Study Shows; Losartan Better Than Atenolol for LVH Treatment; Lisinopril, Not Losartan, Improves Myocardial Perfusion; New Fluoroquinolone Study; Warfarin After MI Better Than Aspirin Alone; FDA News
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Although Japanese encephalitis rarely occurs in travelers, certain groups and subsets of individuals have a risk of infection that can reach 1 in 5000 travelers per week. It is crucial to recognize those with increased risk, and to seriously consider immunizing them in order to prevent the potentially devastating sequelae of Japanese encephalitis.
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Careful evaluation of epidemiologic data from recent African outbreaks of meningococcal disease suggests that significant risks now extend beyond the sub-Saharan belt through the Rift Valley and Great Lakes regions into Mozambique, then into Namibia and Angola.
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Polio-Like Paralysis: What Next from West Nile Virus?; Cat Scratch Disease: Not Just for Kids
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The bacterium Bacillus anthracis causes the death of macrophages, which may allow it to avoid detection by the innate immune system.
