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Among 3602 young adults from coastal Kenya, the overall prevalence of HIV-1 infection was 3.9%. Of 241 patients presenting with fever, 4 patients (1.7%) had acute HIV infection (AHI). 1 of 265 (0.4%) of non-febrile patients had AHI. Malaria was confirmed by PCR in 4 (1.7%) of the febrile patients.
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HIV-infected patients diagnosed with cryptococcal meningitis who received antiretroviral therapy (ART) 5 weeks after starting antifungal therapy had improved survival at 26 weeks compared to similar patients who received ART at 1-2 weeks (45% vs 30%, respectively, P=0.03).
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Compared to manual surveillance methods, an electronic surveillance tool for catheter-associated urinary tract infections had a high negative predictive value but a low positive predictive value.
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The escalating presence of XDR TB in South Africa has created a public health crisis, squeezing already scarce public health dollars. While drug resistant TB represents a small percent of the total TB case load in South Africa, the cost of care for those patients soaked up nearly half of the governments entire TB budget for 2010 (about $126 million USD).
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The current ongoing Ebola virus outbreak in West Africa is the largest ever recorded.
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The Baylor College of Medicine International Pediatric AIDS Initiative at Texas Childrens Hospital created a global health corps named the Pediatric AIDS Corps in June 2005. Over a period of five years, 128 physicians were employed overseas by the Pediatric AIDS Corps with generally high levels of satisfaction and favorable impact on health.
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Antimicrobial prophylaxis reduces the rate of recurrent urinary tract infection in children with vesicoureteral reflux, but it does not alter the rate of renal scarring. Intestinal flora develop antimicrobial resistance in children receiving prophylaxis.
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25 cases of neurologic complications of influenza were reported from Great Britain beginning in 2011. 84% of cases were seen in children. A variety of distinct neurological manifestations were seen. 80% of patients required intensive care, 68% had poor outcomes, and 4 patients (16%) died.
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The first U.S. case of MERS-CoV infection diagnosed in the U.S. has been identified in an individual traveling from Saudi Arabia.