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A total of 1,763 HIV-1 serodiscordant couples in nine countries with the infected partner having CD4+ counts of 350-500/mL were randomized 1:1 to early (immediate) vs. delayed (CD4+ had declined to ¡Ü 250/mL or after development of an AIDS-related illness) antiretroviral therapy of the infected partner.
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Herrera and colleagues reviewed the use of interferon-ã release assays (IGRAs) for the diagnosis of latent tuberculosis infection (LTBI).
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The association of HPV infection and bladder cancer has been a topic of discussion for the last decade, but has not surfaced because of important other outcomes of HPV infection. HPV is increasing in its prevalence globally and its chronic nature raises many issues in and around the genital tract.
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In this issue: ACEI/ARB therapy for AS; safety alert issued for dronedarone; statins and cancer risk; nesiritide and heart failure; and FDA actions.
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"Sand; tiny, discrete particles with substance but basically without fixed structure, frequently accumulating in forms of great beauty or built into 'castles.' In this elemental form sand, and data, present great danger, able to blind us or even bury us." Walter J Hierholzer, Jr., MD
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Katrina Crist, MBA, was recently named the new chief executive officer at the Association for Professionals in Infection Control & Epidemiology in Washington, DC.
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With pathogens like Clostridium difficile and multidrug-resistant Acinebactor which can linger on surfaces and fomites for prolonged periods the health care environment is among the top priority research areas to prevent health care associated infections (HAIs).
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Having finally wrested a seat at the C-suite table, infection preventionists are now poised to move to the patient bedside. A profession that has labored in relative obscurity for much of its existence is at a critical juncture with a host of influential agents who are suddenly very interested in infection prevention: patients, consumer advocates, state and federal regulators. A path to empowerment has opened.
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When a single imported case of measles led to a small outbreak in Tucson, AZ, in 2008, two hospitals were forced to spend a total of some $800,000 to contain it, much of that related to ensuring the immunity of employees.
