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A tripla ® is a branded, combination once-daily tablet recommended as first-line anti-retroviral therapy (ART) for HIV in the United States (containing tenofovir-emtricitabine-efavirenz).
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Seasonal influenza is a major worldwide threat to human health. Vaccination against influenza is an important intervention to prevent disease especially in vulnerable populations, such as the elderly and immunocompromised individuals.
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In this issue: Calcium supplementation in women; type 2 diabetes treatments and pancreatitis risk; treating chronic idiopathic urticaria; rivaroxaban and VTE; and FDA actions.
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A randomized vehicle-controlled phase 3 trial of topical PM 15% vs. PM 15% + GM 0.5% vs. vehicle control was conducted in Tunisian patients with CL due to Leishmania major. 375 patients were randomized. Patients had from 1-5 lesions each. Lesions were treated daily for 20 days.
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Checklists and clear protocols for clinical care have been highly successful in infection prevention and other fields, but can be easily undercut by a simple non-action: silence.
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The broad misconception that infectious diseases were fading as a medical concern with the development of antibiotics and vaccines was dashed in dramatic and tragic fashion in 1981 when the first cases of a strange new illness were reported among groups of gay men in New York, Los Angeles and San Francisco. The AIDS epidemic had begun.
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A randomized, double-blind, placebo-controlled clinical trial was conducted from December 2009 through January 2011 at 18 feeding sites in Malawi. This region of oral sub-Saharan Africa has a subsistence farming population with an estimated 11% of adults infected with the human immunodeficiency virus (HIV).
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Despite notable advances in critical care medicine, mortality from severe sepsis remains unacceptably high. With current therapeutic strategies, nothing has proven more crucial than early and effective antibiotics.
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Human metapneumovirus (HMPV) was only discovered about a decade ago and until this study the extent of the disease — particularly in the young — was not known.
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Doernberg and colleagues sought to determine whether receipt of doxycycline was associated with protection from development of Clostridium difficile infection (CDI) in hospitalized patients being treated with ceftriaxone, a known high-risk antibiotic for CDI.
