HIV/AIDS
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Twice-Yearly Subcutaneous Lenacapavir Injection Prevents HIV Infection
Subcutaneous injection of lenacapavir every 26 weeks had 100% efficacy in preventing human immunodeficiency virus (HIV) infection in a high-risk population.
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A Review of HIV Pre-Exposure Prophylaxis
Human immunodeficiency virus (HIV) pre-exposure prophylaxis is a tool for preventing HIV, especially among high-risk populations. Three medication options are available. Regular screening for HIV and sexually transmitted infections is required, and adherence is crucial for effectiveness. PrEP is underused but increasingly covered by insurance, offering an important preventive option in sexual healthcare.
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Induction Therapy for HIV/AIDS-Related Disseminated Histoplasmosis with Single High-Dose Liposomal Amphotericin B
In a Phase II randomized clinical trial involving 118 participants in Brazil with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS)-related disseminated histoplasmosis, induction therapy with single high-dose (10 mg/kg) liposomal amphotericin B was safe and non-inferior as compared with standard dose (3 mg/kg) liposomal amphotericin B given once daily for 14 days.
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Researchers Address HIV Treatment Gap Among Underserved Population
There are effective medications, but social determinants of health can dictate adherence.
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Infectious Disease Alert Updates
Screening for Chagas in HIV; It’s Not All About the Cough; Linezolid and Cycloserine in CSF Adequate
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WHO Updates Guidance on Long-Acting HIV Prophylaxis
International group suggests adding injectable cabotegravir to list of prevention tools.
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Infectious Disease Alert Updates
Delayed HIV Diagnosis with Injectable PrEP; Fatal Wave of COVID-Associated Mucormycosis
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Is a Cure for HIV Possible Without Stem Cell Transplantation?
In a 30-year-old woman with HIV not on antiretroviral therapy (the “Esperanza patient”), an analysis of 1.188 billion peripheral blood mononuclear cells and 503 million mononuclear cells from placental tissue revealed no genome-intact or replication-competent HIV-1 proviruses. This indicates a sterilizing cure of HIV-1 infection.
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Third Documented HIV Remission Case Emerges
Woman with acute myeloid leukemia underwent stem cell transplant, which apparently sent the virus into remission.
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STI Rates Increasing, but Efficient Testing Can Help
Incidence rates of many sexually transmitted infections (STIs) have increased in the years leading up to the COVID-19 pandemic. There is evidence that STIs have continued to rise during the pandemic, according to the results of a new study.