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In the early 2000s, substantial evidenced-based interventions were added to the care of critically ill patients that significantly reduced mortalityincluding low tidal volume ventilatory support for acute respiratory distress syndrome (ARDS), protocolized sedation with daily awakening, Drotrecogin-alpha for severe sepsis, tight glycemic control, corticosteroids for refractory septic shock and preventative strategies for ventilator associated pneumonia.
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In this prospective observational study, Kollef and associates enrolled patients with ventilator-associated pneumonia (VAP) in 20 ICUs across the United States in order to characterize the patients and the antimicrobial regimens used in treating them, as well as their mortality and lengths of stay.
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In this randomized-controlled trial, Koeman and associates wanted to determine the effect of two oral decontaminating gels, chlorhexidine 2% (CHX) or chlorhexidine 2% plus colistin 2% (CHX/COL), compared to a placebo, on the development of ventilator-associated pneumonia (VAP) in patients requiring more than 48 hours of mechanical ventilation.
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Which Antipsychotics Are More Dangerous?; Should CPOE Undergo Evaluation?; New Treatment for Tennis Elbow; FDA Actions
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The Institute for Healthcare Improvement (IHI) is a not-for-profit organization dedicated to the improvement of health by advancing the quality of health care.
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Critically ill patients with the acute respiratory distress syndrome (ARDS) and/or multi-organ failure pose a challenge in maintaining effective circulatory function while avoiding volume overload.
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Peripherally Inserted Central Venous Catheters (PICCs) are now routinely used in ICUs for long-term central venous access.
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The objective of this study was to test the hypothesis that supplemental oxygen reduces infection risk in patients following colorectal surgery.