The gold standard in the era of EBM is the randomized controlled trial (RCT). A properly designed and carried out RCT, in patients similar to those the practitioner manages and using end points relevant to both practitioner and patient, is more likely to be free from bias and to produce results that will stand up over time than other types of investigation such as retrospective analyses, case-control studies, and unsystematic clinical observations.
Patients who received hyperoxia during general surgery had an increase in surgical site infections compared to those who received a lower oxygen concentration.
New guidelines for the treatment of bacterial rhinosinusitis were published in the January supplement of Otolaryngology-Head and Neck Surgery by the Sinus and Allergy Health Partnership.
Goiter literally means the enlargement of the thyroid gland, independent of its cause. Historically, this terminology specifically was reserved for a visibly enlarged thyroid gland. During the past few decades of modern medical practice, the term has come to include both visible as well as palpable thyroid enlargement. This article will review the pathophysiologic processes leading to goiter formation and will provide a logical approach to the diagnosis and management of different entities, the end result of which is an enlarged thyroid gland.
