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Breast Cancer and the Use of Statins; Warnings Issued for IBS Drugs; FDA Actions
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Several factors are considered to be associated with the development of nosocomial infections in the ICU. Among them, indwelling devices that directly contact the blood and mucosal membrane such as the central venous catheter, urinary tract catheter and endotracheal tube are considered to be the most responsible risk factors in the development of nosocomial infections.
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Among 56,250 British ICU patients, hospital mortality rates were higher among those admitted on the weekend or at night, but the differences disappeared when confounding by illness severity and other aspects of case mix were eliminated.
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This concise review makes a compelling case for a change in the healthcare workers behavior. Helpful hints including increasing the use of alcohol-based formulations to reduce the time constrains are provided throughout the article.
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In late-onset VAP, survival improved and costs decreased using initial coverage with 3 antibiotics. Mini-BAL did not improve survival, but decreased costs and antibiotic usage.
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FDA Rejects Plan B Bid; Recombinant Erythropoietin Products May Stimulate Tumor Growth; Rosuvastatin: Markets Most Potent Statin; FDA Actions.
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This retrospective study determined that catheter-directed thrombolysis was equally effective and safe whether urokinase, alteplase, or reteplase was used, but that costs were substantially less with the newer recombinant drugs.
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In this randomized, controlled trial, when patients developed recurrent respiratory failure following extubation, the use of noninvasive ventilation delayed but did not prevent reintubation, and this delay was associated with a higher mortality rate in the ICU.
