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In late-onset VAP, survival improved and costs decreased using initial coverage with 3 antibiotics. Mini-BAL did not improve survival, but decreased costs and antibiotic usage.
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This concise review makes a compelling case for a change in the healthcare workers behavior. Helpful hints including increasing the use of alcohol-based formulations to reduce the time constrains are provided throughout the article.
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Among 56,250 British ICU patients, hospital mortality rates were higher among those admitted on the weekend or at night, but the differences disappeared when confounding by illness severity and other aspects of case mix were eliminated.
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Several factors are considered to be associated with the development of nosocomial infections in the ICU. Among them, indwelling devices that directly contact the blood and mucosal membrane such as the central venous catheter, urinary tract catheter and endotracheal tube are considered to be the most responsible risk factors in the development of nosocomial infections.
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Breast Cancer and the Use of Statins; Warnings Issued for IBS Drugs; FDA Actions
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Patients who received hyperoxia during general surgery had an increase in surgical site infections compared to those who received a lower oxygen concentration.
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The gold standard in the era of EBM is the randomized controlled trial (RCT). A properly designed and carried out RCT, in patients similar to those the practitioner manages and using end points relevant to both practitioner and patient, is more likely to be free from bias and to produce results that will stand up over time than other types of investigation such as retrospective analyses, case-control studies, and unsystematic clinical observations.
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