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Ova-301 was a large (n = 672), open-label phase III trial comparing pegylated liposomal doxorubicin (PLD) to combination PLD and trabectedin (PT) in women with recurrent ovarian cancer. The trial's overall population was previously reported and demonstrated a significant impact on PFS, without a significant improvement in OS.
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Despite the important progress that has been made in obstetrics, in general, over the last 20 years, shoulder dystocia remains an enigma. Given the rising rate of maternal obesity and gestational diabetes, it is unlikely that the rate of this dangerous complication will be lowered in the near future.
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A recent federal report that included the highly publicized finding that some 15,000 Medicare patients die every month due to adverse events and hospital-acquired conditions (HAC) may ratchet up pressure on hospitals to prevent infections, which represented some 15% of the HACs.
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Group B streptococcal (GBS) disease is the leading cause of early-onset neonatal sepsis (within the first week of life) in the United States. Since the initial recommendations for perinatal prophylaxis in the 1990s, the incidence of GBS has declined by 80%.
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The national epidemic of Clostridium difficile is moving into the pediatric population, causing infections in children that prolong hospitalizations, increase morbidity and spell a striking increase in the risk of death.
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When it comes to MRSA infection control in the chaotic emergency department (ED), enhanced attention to standard precautions and hand hygiene is a more cost-effective approach than active screening cultures, researchers report.
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More health care workers responded to this season's push for influenza vaccination by rolling up their sleeves and getting the vaccine.
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In the H1N1 influenza A pandemic, many infected health care workers failed to wear personal protective equipment. They became sick after caring for infected patients. In addition, they were infected after socializing with co-workers who came to work sick.
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