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Baxter Bioscience has developed a whole-virus, two dose vaccine against avian flu; warning label now on antipsychotics regarding an increased risk of mortality in elderly patients treated for dementia-related psychosis; vitamin D for men with heart disease on horizon? A new oral anticoagulant may soon be available for prevention of thrombotic complications of hip or knee surgery; FDA Actions
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Euthyroid sick syndrome is a reversible abnormality of thyroid function tests in the presence of an acute or chronic nonthyroidal illness (NTI) or an altered physiologic state such as starvation.
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In this review of patients admitted to the ICU with acute respiratory failure secondary to COPD exacerbation or cardiogenic pulmonary edema, nearly two-thirds of patients who apparently met criteria for noninvasive ventilation (NIV) were intubated without a trial of NIV.
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Institution of a daily pharmacist-enforced intervention designed to improve adherence to sedation guidelines decreased the duration of mechanical ventilation and ICU stay.
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Elevated troponin i is a nonspecific finding, but suggests a poor prognosis regardless of its cause.
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Ceftobiprole, a novel broad-spectrum cephalosporin with activity against MRSA, was non-inferior to vancomycin plus ceftazidime in a study of complicated skin and skin-structure infections. This is the first β-lactam with reliable activity against methicillin resistant Staphylococcus aureus (MRSA) to be evaluated in advanced-stage clinical trials.
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Randomized studies of neuroprotective agents for ischemic stroke have resulted in a series of failures, as multiple agents, promising in animal models, have failed when applied to human subjects. By contrast, intracerebral hemorrhage (ICH) has been somewhat a "neglected stepsister" when compared to ischemic stroke; it has been studied minimally, despite its high morbidity and mortality.
