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Perhaps the most prominent cardiovascular report in 2007 was the publication of the COURAGE trial (N Engl J Med. 2007;356:1503-1516), which demonstrated the equality in major CV outcomes in randomized patients with stable CAD, most with angina, who were assigned PCI with optimal medical therapy (OMT) vs OMT alone, with a mean follow-up of 4.6 years.
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A randomized, controlled trial in the Netherlands showed that oral prednisolone and naproxen were equivalent in the treatment of acute gout with no difference in side effects.
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The Babinski sign continues to be a valid bed-side test for pyramidal tract lesions.
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Increased migraine attack frequency and overuse of acute medication, especially barbiturates and opiates, are risk factors for the chronification of migraine, which occurs in up to 2% of individuals.
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Spontaneous subarachnoid hemorrhage (SAH) is associated with high morbidity and mortality.
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The need to prepare families for withdrawal of life support is well known. However, the specific information needed to accomplish this goal is not well defined.
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Noninvasive ventilation (NIV) and continuous positive airway pressure (CPAP) have been shown to be of benefit in the treatment of patients with acute cardiogenic pulmonary edema (CPE).
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In the Issue: Ongoing safety review of tiotropium; raloxifene reduces the risk of endometrial cancer; one-day treatment with famciclovir may be as effective as 3-day treatment with valacyclovir; new Clinical Practice Guideline from the American College of Physicians regarding pharmacologic treatment for low bone density and osteoporosis; FDA Actions.
