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This retrospective analysis of a large number of patients presenting with pulmonary embolism demonstrated that hyponatremia is common in this condition and is an independent predictor of 30-day mortality and hospital readmission.
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Clinicians should consider prescribing levothyroxine at bedtime since this study demonstrates significantly improved thyroid hormone levels compared to morning intake.
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This retrospective cohort study demonstrated that single-dose etomidate administration during rapid-sequence intubation was not associated with adverse outcomes in patients with sepsis or septic shock.
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Anosognosia is an important, but often neglected, part of the neurological examination in a patient with stroke.
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A 84-year-old retired professor was referred for second opinion regarding management of prostate cancer. He had been relatively healthy, with a history of hyperlipidemia and gout.
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Uric acid as a weak organic acid (pka 5.8) is poorly soluble at physiological pH.
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Myelodysplastic syndromes (MDS) usually occur in older adults and, as such, comorbid conditions are common. The investigators found that among 418 MDS patients, at least one comorbid condition existed in 93% at diagnosis. Comorbidity scores were generated using three common scoring systems: the HCT-CI, MDS-CI, and CCI. Worse survival was linked to higher CCI (p = 0.01) and MDS-CI (p = 0.02) but not HCT-CI. Higher CCI scores were associated with non-leukemic death and progression of red blood cell dependency, whereas higher comorbidity by HCT-CI and MDS-CI did not. Higher comorbid burden by CCI in MDS predicts for worse survival and non-leukemic death. Comorbidity data may help refine prognosis for MDS patients.
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Escitalopram for menopausal hot flashes, rifaximin for IBS without constipation, herpes zoster vaccination, antiepileptics drugs and fracture risk, and FDA Actions.
