-
The majority of patients with advanced cancer have decisional capacity at the time of their terminal hospitalization but lose that capacity before having an end-of-life discussion.
-
Patients seen in emergency departments (ED) for acute chest pain who are deemed low risk for acute coronary syndrome (ACS) and relatively safe for discharge are often referred to their primary care physician (PCP) for follow-up.
-
-
Zolpidem and risk of falls; AVR and anticoagulation; statins in cancer patients; and FDA actions.
-
Myocardial perfusion imaging (MPI) refers to the utilization of radiotracers to image regional myocardial perfusion from coronary artery blood flow to the heart muscle. Used effectively, MPI can provide the clinician with a noninvasive technique that yields both important diagnostic and powerful prognostic information regarding the functional significance of anatomic coronary artery disease. MPI can help guide therapeutic decision-making by stratifying patients with respect to future risk for adverse outcomes.
-
Calcium supplementation in women; type 2 diabetes treatments and pancreatitis risk; treating chronic idiopathic urticaria; rivaroxaban and VTE; and FDA actions.
-
-
In this Phase 2 trial, 105 older patients with acute myeloid leukemia who were either treatment-naïve or at first relapse were treated with one of three schedules of oral sapacitabine: 200 mg twice daily for 7 days (group A), 300 mg twice daily for 7 days (group B), or 400 mg twice daily for 3 days each week for 2 weeks (group C).
-
Denosumab is more effective than zoledronic acid at preventing pain in women with advanced breast cancer and bone metastases.
-
In a six-site Italian retrospective analysis, treatment of elderly patients with metastatic renal cell carcinoma with sunitinib was shown to be effective but associated with significant toxicity. Although only applied to a subset, pretreatment comprehensive geriatric assessment did not offer predictive value with regard to severe toxicity or efficacy.
