-
In a review of nine Phase 3 trials enrolling 6,284 patients, data from 793 who were younger than 50 years old were compared to the remainder who were older than 50 years, with attention given to progression-free survival, response rates, and overall survival.
-
A 78-year-old man was referred for evaluation and treatment of recently discovered glioblastoma. While dining with his children he collapsed from his chair and was observed to have a grand mal seizure. He had transiently lost consciousness and when he awoke he had weakness in both upper and lower extremities on the right side.
-
The benefits of cardiac rehabilitation following myocardial infarction (MI) are well known. However, whether these benefits are also seen in ambulant community-based patients who undergo percutaneous coronary intervention (PCI) is not known.
-
Most (83%) patients/surrogates stated they preferred full code status but only 4% could identify the components of CPR; 16% stated preferences that differed with the medical record.
-
Standard therapy for bacterial meningitis in children is probably overkill but it is risky to cut back in resource-rich countries.
-
This randomized study of low-tidal-volume ventilation during and after cardiac surgery, in comparison to ventilation with tidal volumes of 10 mL/kg predicted body weight, showed no differences in median ventilation time but higher rates of extubation by 6 and 8 hours postoperatively and fewer reintubations in the low-tidal-volume group.
-
Using an algorithm based on score and chest X-ray when appropriate, the overall sensitivity for the detection of aortic dissection was 96%.
-
-
In recent months, Escherichia coli O104:H4 has infected more than 4,000 people and caused 880 cases of hemolytic uremic syndrome (HUS) in Europe, with the majority of cases reported in Germany and with more recent outbreaks in France and Switzerland. Travelers should implement food hygiene precautions to prevent infection when visiting Europe.
-
In this issue: Apixaban could soon join the anticoagulation market; Chinese herbs for flu; chronic medication and discontinuation after hospitalization; and FDA actions.