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Aspirin and cancer prevention; rivaroxaban for pulmonary embolism; new rhinosinusitis practice guidelines; and FDA actions.
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A 61-year-old small business owner was seen in consultation for advice regarding management of a newly discovered pulmonary mass. Seven years previously, he had a 3.5 cm moderately differentiated adenocarcinoma of the sigmoid colon resected along with four regional nodes, all of which were negative for metastatic involvement.
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This randomized Phase 3 clinical trial found that adding cetuximab to standard mFOLFOX6 adjuvant chemotherapy did not improve either overall survival or disease-free survival in patients with resected stage III colon cancer, including those with wild-type KRAS tumors.
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Patients who survive admission to the ICU often are left with long-term disabilities resulting both from their presenting illness and from the care they receive while there.
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In this issue: Dementia and benzodiazepines; effectiveness of omega-3 fatty acid and Ginkgo biloba supplements; and FDA actions.
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Although lung-protective ventilation (LPV) is widely acknowledged as one of the few interventions currently available that improves survival in patients with acute lung injury (ALI), it is poorly adopted in practice.
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The purpose of this study conducted in the intensive care department of the Antwerp University Hospital in Antwerp, Belgium, was to determine if the application of earplugs to reduce sound (noise) in the ICU during the night could be beneficial in the prevention of delirium.
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Knowledge of pediatric-specific antimicrobial susceptibility data improves prescribing selections of empiric antibiotic treatment. Providers should advocate for availability of pediatric-specific antimicrobial susceptibility data wherever practical.