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With more effective local therapy achieved by concurrent chemoradiotherapy for patients with advanced squamous cell carcinoma of the head and neck, the occurrence of distant relapse is becoming increasingly observed. In a Phase 2 study, six weekly doses of carboplatin and paclitaxel prior to concurrent chemoradiotherapy resulted in comparable local control and fewer distant relapses when compared to prior studies from this group. The role for induction chemotherapy and the agents selected remains to be established.
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Statins and diabetes risk; new treatment guideline for diabetes; new pertussis vaccine recommendation; antibiotics and rhinosinusitis; fluoroquinolones and cystitis; and FDA actions.
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In survivors of critical illness with documented cognitive impairment at discharge, commonly used cognitive screening tests do not predict which of these patients will experience long-term cognitive impairment.
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Investigators of the stroke arrhythmia monitoring Database in Erlangen, Germany, performed continuous telemetric cardiac rhythm monitoring on 501 acute stroke patients admitted to their stroke unit.
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A history of cancer in a patient with ischemic stroke often raises additional concerns for the clinician, including assessment of cancer activity, as well as possible thrombophilias. The use of thrombolytic agents is also controversial in patients with active cancers.
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Family members who received a diary written during their family members ICU admission had lower levels of symptoms related to post-traumatic stress disorder.
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In the first report (Newland et al), a quasi-experimental study with a control group (also known as a nonrandomized, postintervention design) was performed from 20042010 to determine the impact of an antimicrobial stewardship program (ASP) implemented in March 2008 in a tertiary care childrens hospital that was based on prospective-audit-with-feedback. The control group included 25 childrens hospitals.
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