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Currently, screening for fetal aneuploidy involves a variety of first-line methods that put into play combinations of maternal serum analytes and ultrasound exams in the first and second trimester, with invasive procedures such as chorionic villus sampling (CVS) and amniocentesis being reserved for those at higher risk by history, age, or worrisome results from first-line screening. As will be discussed, each screening combination comes with its own predictive accuracy and now patients and providers can choose from a buffet of screening options, including going right to the main course (amniocentesis or CVS) if one wants 100% accuracy at a small risk of fetal loss (we quote a 1 in 400 risk with amniocentesis and about a 1 in 100 risk for CVS).
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Subjects in the Women's Health Initiative (WHI) trial estrogen-only study randomized to receive conjugated estrogens had a lower incidence of invasive breast cancer than did those who received placebo.
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In this issue: Aspirin and cancer prevention; rivaroxaban for pulmonary embolism; new rhinosinusitis practice guidelines; and FDA actions.
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These authors from Louisiana State University and the University of Hawaii set out to evaluate the quality of information available on the Internet regarding pelvic organ prolapse and urinary incontinence.
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Previous studies have demonstrated the feasibility of identifying sentinel lymph nodes (SLN) in the pelvic and para-aortic nodal basins in women with endometrial cancer.
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Family members of patients recovering from critical illness may experience psychological problems, including anxiety, depression, and post-traumatic stress disorder (PTSD). Jones and colleagues reasoned that provision of an ICU diary, written in everyday language by ICU staff, would be beneficial to family members by providing an explanation of daily events and opportunity for expression of feelings and contribution to the plan of care.
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The cuff-leak test (CLT) was performed prospectively in this study using the volume technique whereby the difference between inspired and expired tidal volume before and after cuff deflation is used to detect the presence of laryngeal edema and the likelihood of developing post-extubation stridor.
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After acute coronary syndromes (ACS), patients remain at risk for recurrent cardiovascular events.
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Doernberg and colleagues sought to determine whether receipt of doxycycline was associated with protection from development of Clostridium difficile infection (CDI) in hospitalized patients being treated with ceftriaxone, a known high-risk antibiotic for CDI.