Results of this well-done trial strongly suggest that CoQ10 administration over 24 weeks' time does not help relieve the treatment-related fatigue experienced by a significant proportion of women with newly diagnosed breast cancer.
Neoadjuvant chemoradiotherapy has become the standard approach for patients with locally advanced rectal adenocarcinoma. For patients who achieve a complete response determined preoperatively, less than maximally aggressive surgery has been contemplated. However, improved accuracy of the preoperative assessment needs to be established. In the current prospective evaluation, assessments of response were made with and without the use of PET/CT in a consecutive series and it was found that the additional scans were useful adjuncts to comprehensive clinical examination.
Medically self-sabotaging behavior encompasses a number of diverse phenomena that include factitious disorder, making medical situations worse on purpose, and preventing wounds from healing.
Celiac disease (CD), also known as gluten-sensitive enteropathy as well as two older and no longer recommended terms,3 nontropical sprue and celiac sprue, is a chronic immune-mediated disorder induced by dietary gluten in genetically susceptible individuals. In CD patients, the ingestion of gluten results in the development of small intestinal mucosal villous atrophy with crypt hyperplasia and mucosal inflammation. Patients may be asymptomatic or may manifest classic malabsorptive symptoms of abdominal pain, bloating, weight loss, diarrhea, and steatorrhea. They also may present along a spectrum with more subtle gastrointestinal and/or extraintestinal symptoms and signs of the disease; virtually every body system can be affected.
In this issue: Side effects of statins; effects of cannabis use; antihypertensives and lip cancer; and FDA actions.
Sentinel lymph node biopsy is an assessment tool for early metastatic nodal spread used in management of many solid tumors.
