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Hematology/Oncology

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  • A new standard of care in the ICU? 'Universal decolonization' cuts BSIs 44%

    In findings that may set a new standard of care in intensive care units, researchers demonstrated in a large-scale trial that a combination of daily chlorhexidine baths and a five-day regimen of nasal mupirocin reduced bloodstream infections (BSIs) for all pathogens by a staggering 44%.
  • Q&A with author of provocative new book

    Martin A. Makary, MD, MPH, an associate professor of surgery and health policy at the Johns Hopkins Hospital in Baltimore, MD is the author of the recently published book "Unaccountable: What Hospitals Won't Tell You and How Transparency Can Revolutionize Health Care."
  • Hospital Infection Control & Prevention November 2012 Issue in PDF

  • Fatal infection in lab worker remains a mystery

    No specific infection control breach has been identified in the death earlier this year of a 25-year-old research laboratory associate at the VA Medical Center in San Francisco.
  • UV light kills bugs on surfaces

    Researchers are finding that a specific spectrum of ultraviolet light kills drug-resistant bacteria and other problem pathogens on common environmental surfaces, including door handles and bedside tables and rails in hospital rooms.
  • Managing Noncancer-related Chronic Pain Without Opioids

    Managing chronic pain is a challenge for patients and clinicians alike, with 52% of chronic pain patients being treated solely by their primary care physician.1 Chronic myofascial pain affects 116 million American adults, which is more than heart disease, cancer, and diabetes combined.2
  • Clinical Briefs in Primary Care Supplement

  • PET/CT as Tool in Assessing Response to Neoadjuvant CRT for Rectal Cancer

    Neoadjuvant chemoradiotherapy has become the standard approach for patients with locally advanced rectal adenocarcinoma. For patients who achieve a complete response determined preoperatively, less than maximally aggressive surgery has been contemplated. However, improved accuracy of the preoperative assessment needs to be established. In the current prospective evaluation, assessments of response were made with and without the use of PET/CT in a consecutive series and it was found that the additional scans were useful adjuncts to comprehensive clinical examination.
  • No 'Go' with CoQ10 for Treatment-Related Fatigue

    Results of this well-done trial strongly suggest that CoQ10 administration over 24 weeks' time does not help relieve the treatment-related fatigue experienced by a significant proportion of women with newly diagnosed breast cancer.
  • Waldenström Macroglobulinemia with Hyperviscosity

    A 57-year-old retail pharmacist presented to his primary care physician because of progressive headaches, blurry vision, hearing loss, and episodes of confusion. He had not had night sweats, fever, or weight loss. On physical examination he was found to be pale and there were ecchymoses over his upper and lower extremities that he reported occurred spontaneously over the past 3 months. He had attributed these to his current medications including both aspirin (81 mg/day) and clopidogrel (75 mg/day), although he had been taking these medications for more than 5 years without noticing ecchymoses in the past. He did not have palpable lymphadenopathy nor was there splenomegaly.