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In this issue: Lorcaserin for weight loss; statins and fatigue; treatment-resistant gonorrhea; hydrocodone classification changes; USPSTF recommendations; and FDA actions.
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Apropos of the recent emphasis on discouraging elective deliveries prior to 39 weeks, a group from Cincinnati embarked on a study to determine whether steroids had any neonatal benefit in patients delivering between 34 and 39 weeks who had immature amniotic fluid lung profiles.
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The authors performed a prospective cohort study, the contraceptive CHOICE Project, in which women in the St. Louis, Missouri, region received a reversible contraceptive method of their choice for up to 3 years at no cost.
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To provide guidance to clinicians on the use of hormone replacement therapy, the authors conducted a systematic review of the randomized, placebo-controlled trials of menopausal hormone therapy published in English since 2002 that assessed primary prevention of chronic conditions.
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Poly(adenosine diphosphate [adp]-ribose) polymerase (PARP) is an enzyme participating in low-fidelity DNA repair of single strand breaks. Pharmacologic inhibition of PARP has shown to be effective in tumors lacking homologous recombination, such as those harboring silencing mutations of BRCA1 and 2.
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Researchers from duke university and the university of California, San Francisco enrolled 40 patients with symptoms of overactive bladder (OAB), i.e., urgency, frequency, and/or urge incontinence, and 40 patients with no history of OAB symptoms. The women's view of symptoms and treatments were measured with a utility score.
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Increasingly common across the health care landscape, construction and renovation can make patient safety challenging. The need to expand facilities or upgrade existing space creates dust and particles that can easily become aerosolized, potentially transporting infectious Aspergillus and other fungal and bacterial organisms toward vulnerable patient populations.
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The Centers for Medicare and Medicaid Services (CMS) controversial plan to survey the nation's hospital infection control programs is drawing fire for both going beyond its regulatory authority in some areas and not mandating more specific infection prevention resources in others.
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Ventilator associated pneumonia (VAP) rates have dropped significantly in a level II adult neuro/trauma unit at Essentia Health System in Duluth, MN, largely as a result of the unit following this six-step intervention: