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Data were accessed from the nurses health study, which enrolled 121,700 U.S. female registered nurses who were 30-55 years old at the outset in 1976. Every 2 years, participants provided information about their lifestyle, medical history, and illnesses via mailed questionnaires.
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In this issue: Zolpidem and risk of falls; AVR and anticoagulation; statins in cancer patients; and FDA actions.
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The authors performed a nested case-control study using data from the Rochester Epidemiology Project which conducts population-based studies of the residents of Olmsted County, Minnesota.
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A 62-year-old Caucasian woman returns to her primary care physician for a follow-up visit after routine colonoscopy and is accompanied by her 63-year-old husband. The gastroenterologist had resected three adenomatous polyps and suggested a repeat colonoscopy in 1 year.
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Among women with early-stage squamous cell carcinoma of the vulva, sentinel node biopsy is a reasonable alternative to inguinal femoral lymphadenectomy. Histological ultrastaging is an important adjuvant to sentinel node assessment for metastatic disease.
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Dementia and benzodiazepines; effectiveness of omega-3 fatty acid and Ginkgo biloba supplements; and FDA actions.
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In a series of consecutive patients with locally advanced rectal cancer, a novel treatment regimen was studied that involved "induction chemotherapy" followed by chemoradiotherapy prior to total mesorectal excision. The investigators found a high local control rate and promising disease-free and overall survival outcomes.
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There has long been an appreciation of the risk of cognitive decline associated with chemotherapy but questions remain about the magnitude and duration of the observed deficits. In this meta-analysis of studies that included neuropsychological assessments at a minimum of 6 months after completion of breast cancer chemotherapy, definite but small deficits were found for both verbal and visuospatial capabilities. In this analysis, age and educational status were not found to be moderators of acquired deficits.
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Women who last give birth at age 40 or older have a 44% decreased risk of endometrial cancer when compared to women who have their last birth under the age of 25, according to results of a new international study.1