-
In an attempt to clarify criteria for diagnosing adrenal insufficiency in patients with severe sepsis and septic shock, this group of French investigators serially performed both the cosyntropin stimulation test and the metyrapone stimulation test in 2 cohorts of such patients, and compared the findings with those from concurrent ICU patients without sepsis as well as a group of healthy volunteers.
-
A few weeks ago a technical representative of one of the leading ICU ventilator manufacturers gave an "in-service" presentation to the leaders of the respiratory care department at my institution.
-
-
-
Imatinib inhibits the BCR/ABL tyrosine kinase in CML, leading to improved responses over standard therapy. This report provides 5 year follow-up from the seminal IRIS study of upfront imatinib for chronic phase CML among the 553 patients randomized to 400 mg of imatinib.
-
Trastuzumab has previously been demonstrated to be active against HER2 positive breast cancer when used in the metastatic setting.
-
In a family-based research cohort, men were followed for up to 40 years after the birth of their children, and those with only daughters had a 40% higher risk of prostate cancer compared with men with at least one son.
-
Breast cancer statistics indicate a rapid decrease in prevalence immediately after the publicity surrounding the reports from the Women's Health Initiative.
-
Breast cancers that are "triple-negative" (ie, ER, PR, HER2-negative) are considered high risk, yet there remains variability, with some demonstrating less malignant features than others.
-
Several important papers have been published in the last 2 months, none more important than the realization that breast cancer rates have dropped precipitously since the publication of the Women's Health Initiative (WHI) in 2002.
