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In an attempt to clarify criteria for diagnosing adrenal insufficiency in patients with severe sepsis and septic shock, this group of French investigators serially performed both the cosyntropin stimulation test and the metyrapone stimulation test in 2 cohorts of such patients, and compared the findings with those from concurrent ICU patients without sepsis as well as a group of healthy volunteers.
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Herbal Supplements to Treat Vasomotor Symptoms; Bisphosphonates to Treat LBD, After 5 Years?; FDA Actions
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Mechanical ventilation has been evolving ever since the introduction and large scale use of iron lungs. Advances in the fields of medicine and technology have resulted in nearly an alphabet soup of modes of mechanical ventilation.
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An elderly man is found hypothermic and unresponsive in a bus station, and is brought by paramedics to the nearest hospital.
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Several important papers have been published in the last 2 months, none more important than the realization that breast cancer rates have dropped precipitously since the publication of the Women's Health Initiative (WHI) in 2002.
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Breast cancers that are "triple-negative" (ie, ER, PR, HER2-negative) are considered high risk, yet there remains variability, with some demonstrating less malignant features than others.
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Breast cancer statistics indicate a rapid decrease in prevalence immediately after the publicity surrounding the reports from the Women's Health Initiative.
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In a family-based research cohort, men were followed for up to 40 years after the birth of their children, and those with only daughters had a 40% higher risk of prostate cancer compared with men with at least one son.
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Trastuzumab has previously been demonstrated to be active against HER2 positive breast cancer when used in the metastatic setting.