Hematology/Oncology
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Ethical Problems with Rural Cancer Patients’ Access to Care
Patients and clinicians should discuss any available data regarding differences in care delivered at potential treatment sites, potential accompanying outcomes differences, and the costs and benefits of pursuing treatment at each site. Rural patient navigators should be involved in this discussion, considering the complexity of care coordination for patients with cancer.
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Increasing Incidence of Stage IV Cervical Cancer
The incidence of stage IV cervical cancer in the United States between 2001 and 2018 increased. Rates were highest among Black women, but the annual rate of increase was highest among white women in the South age 40-44 years.
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MicroRNA Could Help Oncologists Craft Better Treatment Plans for Breast Cancer Patients
Researchers have been searching for biomarkers that are good predictors of cancer recurrence and mortality.
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Updated Recommendations on Pediatric End-of-Life Care
A report includes a review of essential elements of care for patients and families. The authors covered discussions on goals of care, how to establish end-of-life care goals, advance care planning, and palliative and hospice involvement.
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Betibeglogene Autotemcel Suspension (Zynteglo)
The FDA has approved the first cell-based gene therapy to treat adult and pediatric patients with beta-thalassemia who require regular blood transfusions.
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Parents, IRBs Hold Different Views on Phase I Pediatric Oncology Trials
IRB members are more likely than the public to think the risks outweigh the potential medical benefits. Parents think about the possibility of caring for a child with severe cancer and no treatment alternatives. IRBs ensure trials are ethical and that pediatric subjects are not exposed to excessive risk.
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HPV Vaccination in Adolescence Prevents Cancer More than 10 Years Later
In a study of human papillomavirus (HPV) vaccination, researchers evaluated cancer protection over up to 11 years of follow-up. During this time, the authors noted 100% vaccine efficacy at preventing HPV-associated cancers.
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Cancer Death Rate for Black Americans Declines, Remains Higher Than That of Other Groups
Rapid declines in deaths from lung and stomach cancers parallels rise in mortality from uterine and liver cancers.
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The Association Between Cancer Mortality and Physical Activity for Middle-Aged and Older Patients
In a prospective cohort study of older U.S. adults, replacing sedentary behavior with physical activity was associated with a lower cancer mortality risk.
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Postmenopausal Estrogen May Prevent Death from COVID-19 Infection
Swedish researchers found taking postmenopausal estrogen was associated with a lower death rate from COVID-19 infection. Taking estrogen suppression therapy for breast cancer was associated with a higher death rate compared with controls.