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Because of adverse effects, special care should be used when prescribing the atypical antipsychotic drugs for patients with dementia.
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Salvage therapy of invasive aspergillosis with posaconazole was associated with a 42% response rate, compared to only 26% in an external control group.
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Using the metyrapone test as a gold standard, the authors confirmed that a resting serum cortisol level < 10 micrograms/dL, or an increase of < 9 micrograms/dL after cosyntropin stimulation, accurately diagnoses adrenal insufficiency in ICU patients with severe sepsis or septic shock.
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In a study involving 108 ICUs in Michigan, an evidence-based intervention led to a 66% reduction in catheter-related bloodstream infections that was sustained over an 18-month period.
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Searching Google yielded a correct diagnosis in greater than half of cases.
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A multicenter, observational study retrospectively compared 59 individuals with acute or early HIV infection who elected to receive antiretroviral (ARV) therapy for 12 weeks to 337 patients who declined treatment.
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The explosion of infection rate disclosure laws in recent years caught the health care epidemiology community so off guard, the metaphor used at many early meetings on the phenomenon was that "the train has left the station."
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A "tool kit" created by an expert panel on hospital infection reporting laws recommends that health care worker influenza vaccination rates be included as a quality measure and that workers refusing immunization be required to sign declination forms.
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Pronovost and colleagues conducted a multi-hospital cohort study aimed at reducing the rate of catheter-related bloodstream infections (CRBSIs) in ICUs. The intervention focused on increasing adherence to evidence-based CDC recommendations for catheter insertion. In summary, these are:
