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Obesity and the magnitude of nocturnal oxygen desaturation, which is an important pathophysiological consequence of OSA, are independent risk factors for incident AF in individuals <65 years of age.
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In the institution in which this study took place, an audit revealed that adherence to 9 ICU protocols ranged from 62% to 77%. The protocols focused on a variety of patient care needs including sedation/analgesia, DVT prophylaxis, enteral nutrition, insulin administration, skin care, stress ulcer prophylaxis, and ventilator weaning.
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Building on the results of previous pilot studies from their laboratory and a meta-analysis that showed a tendency toward improved mortality in critically-ill patients following selenium administration, Angstwurm and colleagues used a randomized, placebo-controlled multi-center trial to determine whether intravenous administration of selenium could improve outcomes in severe sepsis and septic shock.
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Many of the recent advances in intensive care have been the product of large clinical trials. Over the years, randomized studies have demonstrated agents and modalities that impact survival of our sickest patients.
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Inhaled bronchodilators are the cornerstone of managing acute airway obstruction, and their use in intubated, mechanically ventilated patients with asthma and COPD is a standard of care.
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Trauma surgeons at 21 institutions participated in this retrospective study of inferior vena cava filter (IVCF) placement and follow-up. A total of 599 IVCFs were placed at the 21 hospitals during the study year, 226 (0.8% of all admissions) at the 7 high-volume hospitals (> 2000 trauma cases admitted), and 373 (2% of all admissions, P = 0.009) at the 14 low-volume institutions.
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IBS-Drug Treatment Pulled, CV Side Effects; Drug Combo Better for Migraine Treatment; Pergolide Off the Market, Heart Disease Risk; Hormone Treatment, Does Timing Matter?; FDA Actions
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Status epilepticus, in the setting of cancer, is treatable and does not appear to increase mortality above the risk of the underlying disease.