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The new guidelines recommend antibiotic prophylaxis of infective endocarditis in a much more restricted group of patients than did previous guidelines.
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This multicenter, randomized, double-blind, placebo-controlled trial finds that early initiation of low-dose, prolonged glucocorticosteroid therapy for ARDS results in improved lung injury scores and a greater likelihood of successful extubation by day 7.
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Standard 10-day triple therapy for Helicobacter pylori may result in relatively low eradication rates.
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A meta-analysis of 18 studies that have examined the usefulness of procalcitonin measurement in the diagnosis of sepsis finds that the diagnostic performance of this measurement is low and that the test cannot reliably distinguish sepsis from other causes of the systemic inflammatory response syndrome.
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MRI is more sensitive than CT for detecting acute ischemia and can detect acute hemorrhage with equal sensitivity to CT.
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The literature on the technical and clinical aspects of mechanical ventilation for patients with acute respiratory failure continues to expand, with nearly 50,000 citations appearing in PubMed for the topic "mechanical ventilation," and more than a thousand articles in English reporting the results of clinical trials under this heading published during the last 5 years.
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The objective of this study was to evaluate the role of patient-ventilator dys-synchrony in the etiology of sleep disruption, and to determine whether optimizing patient-ventilator interactions by using proportional assist ventilation (PAV) improves sleep.
