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In this issue: Drug combinations for hypertension; tenecteplase for out-of-hospital cardiac arrest; CAM most commonly used for back, neck, and arthritis pain; FDA Actions.
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A randomized, double-blind, placebo-controlled trial comparing Ginkgo biloba with placebo for the prevention of dementia enrolled 3069 elderly individuals (older than age 75) in 5 academic centers in the United States.
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A 3-year randomized, double-blind clinical trial in 206 sites throughout the world compared bazedoxifene (20 mg or 40 mg) and raloxifene (60 mg) with placebo.
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Cromer et al performed a 24-month observational, prospective cohort study of adolescents in the Midwest using depot medroxyprogesterone acetate (DMPA), oral contraceptives (OCs), or nothing. DEXA scans were performed at baseline and 6-month intervals.
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The above study involved a detailed analysis of data obtained in the observational arm of the Women's Health Initiative. As a rationale, the authors note that obesity is a well-established risk factor for breast cancer.
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The stars were aligned when four papers appeared in two obstetrical journals within a month of each other dealing with the optimal time in gestation to deliver.
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This issue deals with a common but often frustrating and unrewarding condition that confronts primary care physicians: fibromyalgia.
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