Hematology/Oncology
RSSArticles
-
Sacubitril/Valsartan Associated with Reduced Risk of Hyperkalemia
\In a secondary analysis of the PARADIGM-HF trial, the risk of severe hyperkalemia in heart failure patients taking a mineralocorticoid receptor antagonist was lower among patients treated with sacubitril/valsartan compared to those receiving enalapril.
-
Zika Virus Infection and Guillain-Barré Syndrome: The Evidence Grows
A recent Zika outbreak in Colombia was associated with a significant increase in Guillain-Barré syndrome (GBS) rates, with laboratory evidence of definite or probable Zika infection in more than half of the GBS cases.
-
Early Initiation of Continuous Renal Replacement Therapy May Reduce Mortality in Patients Who Require Dialysis
Initiation of continuous renal replacement therapy for patients with Kidney Disease: Improving Global Outcomes stage 2 renal failure reduced 90-day all-cause mortality.
-
Bezlotoxumab Injection (Zinplava)
The FDA has approved a selective, fully human monoclonal antibody directed at Clostridium difficilie toxin B. Binding of toxin B neutralizes its toxic effect. Bezlotoxumab is marketed as Zinplava.
-
Fecal Transplant vs. Oral Vancomycin Taper for Recurrent Clostridium difficile Infection
In a small randomized, controlled trial that compared fecal microbiota transplant (FMT) administered by enema to a six-week oral vancomycin taper, FMT was not more effective for patients with recurrent Clostridium difficile infection. -
High-flow Nasal Cannula vs. Noninvasive Ventilation in Postextubation Failure
SYNOPSIS: In this multicenter, randomized, clinical trial of critically ill adults at high risk for reintubation, high-flow conditioned oxygen therapy was not inferior to noninvasive mechanical ventilation with regard to preventing reintubation and postextubation respiratory failure within 72 hours of extubation.
-
Diastolic Blood Pressure Goals
SYNOPSIS: An analysis of the community-based ARIC study showed that low diastolic blood pressures were associated with higher baseline and subsequent troponin T levels and adverse cardiac events, but not stroke.
-
Pulmonary Embolism Common Cause for Syncope in Hospitalized Patients
Syncope is a chief complaint for which neurologists often are consulted. In most cases, the neurological concern is possible stroke or an epileptic seizure. However, a variety of cardiopulmonary problems are most often the underlying cause of syncope, including cardiac arrhythmias and pulmonary embolism. The investigators of this study reviewed the clinical records of 560 patients (mean age of 76 years) who were admitted to the hospital with syncope.
-
New Paradigm in the Management of Massive and Submassive Pulmonary Embolism
SYNOPSIS: A multidisciplinary pulmonary embolism response team is a sustainable option to improve care for severe pulmonary embolism.
-
VRE and MRSA: Should We Stop Routine Contact Precautions?
SYNOPSIS: The value of routine contact precautions for VRE and MRSA is strongly challenged.