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In former, aging, National Football League players, fluid-attenuated inversion recovery scans showed increased total and deep white matter hyperintensity volumes, while diffusion tensor imaging showed decreased fractional anisotropy reflecting white matter disruption, and this is associated with cognitive impairments and depression.
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Children with intracerebral hemorrhage are at increased risk for seizures and epilepsy compared to adults, particularly those who develop elevated intracranial pressures.
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The combination of interferon beta 1a (30 mcg IM weekly) and glatiramer acetate was not more effective on annualized relapse rate in multiple sclerosis compared to either treatment alone.
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In a study of the elderly who are normal or have mild cognitive impairment, vascular brain disease and brain amyloid deposition appear to be independent risks for dementia.
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Nocturnal calf cramps are usually benign and respond to stretching and muscle-strengthening exercises.
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Beta-blockers and noncardiac surgery; prenatal medication exposure and risk of autism; reasons for statin discontinuations; and FDA actions.
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Almost a third of children and adolescents seen in the emergency department with mild traumatic brain injury develop postconcussion syndrome, with migraine-like headaches as the most common symptom.
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After successful treatment of sciatica, routine follow-up MRI of the lumbar spine provides no useful information. Recurrent or persistent symptoms mandate additional evaluation based on clinical symptoms and signs.
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Chelation therapy for cardiovascular disease; statins and kidney injuries; chlorthalidone for hypertension; and FDA actions.
