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Inflammation is thought to play a role in alzheimers disease (AD) pathogenesis. Evidence of inflammation is seen in AD brains, including activated microglia, cytokines, and complement components.
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Juvenile myoclonic epilepsy (jme), sometimes called Janz syndrome, is the most common idiopathic generalized epilepsy and is characterized by multiplicity of seizure types, including myoclonic jerks on awakening, generalized tonic-clonic seizures, and absence seizures.
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Intravenous (IV) or intra-arterial treatment with tissue plasminogen activator (tPA) and mechanical clot extraction can limit the damage that some ischemic strokes cause, but they also can cause complications, including hemorrhage into established infarcts.
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Herpes simplex virus encephalitis (HSE) is the most common cause of sporadic fatal viral encephalitis. Although the mortality and morbidity of HSE has been significantly reduced due to early antiviral therapy, even after treatment, about 35% of patients have severe neurological sequelae or even death.
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In this issue: Aspirin use and AMD risk; using NSAIDs and antihypertensive agents; and FDA actions.
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Do the presence or absence of acetylcholine receptor (AchR)-binding antibodies (Abs) and muscle-specific kinase (MuSK) Abs correlate with disease phenotype in myasthenia gravis (MG)?
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Chesnut et al have performed the first randomized, controlled trial to evaluate the benefit of intracranial pressure (ICP) monitoring on outcome after severe traumatic brain injury (TBI).
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Although many children with a first febrile seizure will have had a simple febrile seizure, a relatively common and benign childhood illness, a subset will present in febrile status epilepticus, the most severe in the spectrum of febrile seizures.
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In this issue: Apixaban approval; new dental clinical practice guideline; apixaban for VTE; aspirin resistance; tamoxifen treatment; and FDA actions.
