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Early cessation of prehospital seizures via an intramuscular injection of midazolam was at least noninferior, if not superior, to traditional intravenous lorazepam.
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In comatose survivors of cardiac arrest, early malignant EEG findings during therapeutic hypothermia correlated with higher serum neuron-specific enolase levels and poor neurologic outcome.
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Krabbe disease can rarely present in adults as a combined central nervous system disorder with polyneuropathy.
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Continuation of combination therapy with donepezil and memantine appears to have a long-term beneficial effect for patients with moderate-to-severe Alzheimer's disease.
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Aspirin and cancer prevention; rivaroxaban for pulmonary embolism; new rhinosinusitis practice guidelines; and FDA actions.
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When a brain biopsy is being considered for a nonmalignant condition, the patients and the site of biopsy must be carefully selected to ensure the most useful results.
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Antihypertensive treatment reduces the incidence of headache compared to placebo, but the magnitude of the effect differs between drug classes independent of the magnitude of blood pressure reduction. Dysautoregulation in the anterior and posterior circulation is associated with migraine with aura.
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In a post-hoc analysis, rasagiline, as an adjunct to levodopa, is both efficacious in reducing "off" time and well-tolerated in individuals older than 70 years with moderate-to-advanced Parkinson's disease.
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Necrotizing myositis is a newly described inflammatory myopathy that has an autoimmune etiology and may be associated with anti-signal recognition particle autoantibodies.