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In this issue: Statins and diabetes risk; new treatment guideline for diabetes; new pertussis vaccine recommendation; antibiotics and rhinosinusitis; fluoroquinolones and cystitis; and FDA actions.
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It has been long recognized that thrombocytosis (defined as a platelet count > 450,000/mm3) frequently accompanies the diagnosis of advanced cancer and has been associated with poor outcomes.
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The authors conducted a double-blind, randomized, controlled trial to determine whether the postoperative use of a levonorgestrel intrauterine system (LNG-IUS) was an effective treatment for chronic pelvic pain in women with endometriosis.
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Managing labor is an art, while the actual delivery process requires the addition of skill and experience. Yet, the decision of which route of delivery to employ may have the greatest impact on outcome. A recent article deals with neonatal morbidity, including an important contributor, intracranial injury, and its association with various forms of operative delivery.
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In this study, 4957 women aged 67 and older were followed prospectively for up to 15 years. Statistical models were used to calculate the bone mineral density (BMD) testing interval for women with normal BMD and those with mild, moderate, or advanced osteopenia.
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New treatment for TB; safety of dabigatran; quality of antidepressants; systolic hypertension treatment; and FDA actions.
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A 57-year-old postmenopausal librarian, who is 1-year post diagnosis of a stage II invasive cancer of the right breast, is found to be estrogen- and progesterone-receptor positive, and Her2neu negative with one positive axillary node.
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A full panel of prognostic indicators was examined in 449 treatment-naïve CLL patients and it was found that serum light chain ratio was useful in confirming clonality. However, the sum of both k and l serum light chains proved of greater prognositc value in determining an early need to offer CLL treatment. A total (k + l) level of > 60.6 mg/mL was an independent predictor of limited treatment-free survival.