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Look for new labeling on combined oral contraceptives (OCs) containing drospirenone following the Food and Drug Administration's (FDA) review of studies regarding the risk of blood clots in women using such formulations.
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Pre-exposure prophylaxis (PrEP) for HIV prevention has taken a giant step forward with a Food and Drug Administration (FDA) committee's recommendation for approval of a specific drug for such use.
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In 1992, reproductive health advocates estimated that widespread use of emergency contraceptive pills (ECPs) could prevent half of all U.S. unintended pregnancies and abortions.
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In a large retrospective series, 2051 men with clinically localized prostate cancer received definitive radiation therapy (RT) alone. The rates of aspirin use and statin use were 36% and 34%, respectively. The primary endpoint was IBF (interval to biochemical failure) of < 18 months.
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By a systematic review of observational (case-control and cohort) studies, data regarding aspirin use and cancer risk were compared to data obtained from randomized clinical trials. In general, there was very good correlation regarding reduced risk for several types of cancer and the development of metastatic disease. The analysis provides confidence that observational studies can be of value in addressing the many outstanding questions regarding aspirin and cancer prevention.
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A 64-year-old commercial airline pilot was seen by his primary physician because of a bothersome, non-productive cough. He has a history of asthma but requires no medications other than occasional albuterol inhalation. Physical examination was unremarkable, as were the complete blood count and chest x-ray.
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This randomized, placebo-controlled, Phase 3 clinical trial showed that the majority of patients treated with pegfilgrastim experience bone pain, and that taking 500 mg of naproxen twice a day decreases its incidence and severity.
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Azithromycin and cardiac risk; warfarin and heart failure; aspirin and VTE; effectiveness of long-acting contraceptives; and FDA actions.
