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The above study involved a detailed analysis of data obtained in the observational arm of the Women's Health Initiative. As a rationale, the authors note that obesity is a well-established risk factor for breast cancer.
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Cromer et al performed a 24-month observational, prospective cohort study of adolescents in the Midwest using depot medroxyprogesterone acetate (DMPA), oral contraceptives (OCs), or nothing. DEXA scans were performed at baseline and 6-month intervals.
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A 3-year randomized, double-blind clinical trial in 206 sites throughout the world compared bazedoxifene (20 mg or 40 mg) and raloxifene (60 mg) with placebo.
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A randomized, double-blind, placebo-controlled trial comparing Ginkgo biloba with placebo for the prevention of dementia enrolled 3069 elderly individuals (older than age 75) in 5 academic centers in the United States.
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In this issue: Drug combinations for hypertension; tenecteplase for out-of-hospital cardiac arrest; CAM most commonly used for back, neck, and arthritis pain; FDA Actions.
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Of 34 breast cancer patients with pulmonary nodules and no other evidence for metastatic disease, progression occurred in only 3 (of the 26) whose nodules were < 1 cm in diameter, compared with all 8 in whom the nodules were > 1 cm.
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Options for CML blast phase after imatinib failure have been very limited.
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In a post hoc analysis of patients entered on a prostate cancer clinical trial, among those receiving androgen suppression therapy, those with higher levels of comorbidity were more likely to suffer adverse consequences, and this was particularly evident for those who had lower risk for prostate cancer specific mortality.
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A European multi-institutional trial compared outcome in terms of three-year disease-free and overall survival for patients with colon cancer who had resection either by laparoscopic approach or laparotomy.
