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A 84-year-old retired professor was referred for second opinion regarding management of prostate cancer. He had been relatively healthy, with a history of hyperlipidemia and gout.
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Uric acid as a weak organic acid (pka 5.8) is poorly soluble at physiological pH.
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Myelodysplastic syndromes (MDS) usually occur in older adults and, as such, comorbid conditions are common. The investigators found that among 418 MDS patients, at least one comorbid condition existed in 93% at diagnosis. Comorbidity scores were generated using three common scoring systems: the HCT-CI, MDS-CI, and CCI. Worse survival was linked to higher CCI (p = 0.01) and MDS-CI (p = 0.02) but not HCT-CI. Higher CCI scores were associated with non-leukemic death and progression of red blood cell dependency, whereas higher comorbidity by HCT-CI and MDS-CI did not. Higher comorbid burden by CCI in MDS predicts for worse survival and non-leukemic death. Comorbidity data may help refine prognosis for MDS patients.
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Escitalopram for menopausal hot flashes, rifaximin for IBS without constipation, herpes zoster vaccination, antiepileptics drugs and fracture risk, and FDA Actions.
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Your next patient is a young woman who was in two months ago for a chlamydia infection. You provided her with a prescription and asked that she have her partner come in for evaluation, testing, and treatment.
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What is your practice when it comes to screening women for chlamydia? The Centers for Disease Control and Prevention (CDC) recommends annual chlamydia screening for all sexually active young women age 25 and younger.
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While it is not in the top tier of contraceptive effectiveness, the diaphragm remains an option as a female-controlled method of birth control. What do you know about this form of family planning?
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Many women might choose the contraceptive injection depot medroxyprogesterone acetate (DMPA, Depo-Provera) for its ease of use, but they might discontinue the method due to irregular bleeding.
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Findings from a new national report reflect an increase in the use of early medication abortion.
