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Chromosome banding analysis (CBA) of marrow metaphase cells is the standard method to assess response in CML. The authors compared CBA to interphase fluorescence in situ hybridization (I-FISH) in 664 samples where both methods were performed.
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A long-term longitudinal assessment of quality of life among patients treated for early-stage Hodgkin's lymphoma reveals that, with the exception of fatigue, there is general improvement over time. Factors that influence the rate of improvement include age and sex, but do not include the type of treatment received (radiation vs. chemotherapy).
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In a large population-based, prospective cohort study, it was found that spending less than 50% of the day in a sedentary position, and increasing amounts of physical activity (e.g., walking or bicycling) appear to be associated with reduced rates of prostate-cancer development.
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This meta-analysis revealed overall increased mortality of up to 25% in patients experiencing depressive symptoms after cancer diagnosis, and a 39% higher risk in patients diagnosed with major or minor depression after cancer diagnosis, based upon 25 independent studies. Given the low number of studies available to date, the effect of depressive symptoms on cancer recurrence did not reach a level of statistical significance.
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Statin and niacin increase HDL-C, omeprazole reduces effectiveness of clopidogrel, darbe-poetin increases risk of stroke, statins decrease risk of gallstone disease, FDA Actions.
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In a retrospective tumor registry (SEER) analysis of outcomes for rectal-cancer patients treated over a 14-year period with either presurgical or postsurgical radiation therapy, the importance of pathological lymph node status was found to be significantly more adverse for patients who had presurgical treatment. These patients define a subgroup for whom aggressive post-surgical treatment would seem warranted.
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Your next patient in the clinic examination room is a 22-year-old who has just delivered her first child three weeks ago.
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With Congress edging closer to enacting broad health care reform legislation, questions abound about its potential impact on patients and providers.
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This issue marks the 30th anniversary of Contraceptive Technology Update.
