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A previously reported, industry-sponsored phase 3 trial showed improvements in progression-free survival, objective response, and a non-significant trend toward increased overall survival with panitumumab-FOLFIRI vs FOLFIRI alone for second-line wild-type KRAS metastatic colorectal cancer.
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Using the SEER database, this report examined 1926 patients aged ≥ 70 years who were diagnosed with limited-stage small cell lung cancer between 1988 and 1997.
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Long-term complications, particularly secondary cancers, were significantly more common in patients receiving whole pelvic radiation (vs brachytherapy alone) for early-stage endometrial cancer.
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For patients with BRCA-associated breast cancer, it had been previously demonstrated that a second breast cancer occurs in approximately one-third of patients by 15 years after diagnosis, and that this risk was reduced significantly by contralateral mastectomy.
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Bevacizumab added to chemotherapy, particularly paclitaxel and cisplatin, was efficacious in all response outcomes (objective response, progression-free survival, and overall survival) without diminution in quality of life or unacceptable toxicity.
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In a well-controlled retrospective analysis of patients who presented with metastatic colorectal cancer, primary tumor resection was associated with improved overall survival.
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In a multicenter, randomized, double-blind, placebo-controlled clinical trial of bevacizumab added to standard temozolomide and radiation therapy for patients with glioblastoma multiforme, progression-free survival but not overall survival was enhanced.
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We now have three options for emergency contraception the copper IUD, oral ulipristal acetate, and oral levonorgestrel. One of the most important considerations in using emergency contraception is the initiation of ongoing regular contraception. The special feature will discuss the opportunities and considerations for use of these three different methods of postcoital contraception.
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A meta-analysis of 19 studies involving first trimester screening for fetal anomalies has shown that a majority of major structural abnormalities can be diagnosed between 11 and 14 weeks and that even cardiac abnormalities can be identified with ultrasound with reasonable efficiency.
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Synopsis: In this study, women without allergies who consumed peanuts or tree nuts five times or more per month around the time of pregnancy compared to less than one time per month had reduced odds of having children with peanut or tree nut allergies.
