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In this issue: Medication poisonings in children; rosuvastatin vs atorvastatin for atherosclerosis; saw palmetto for prostate symptoms; using atypical antipsychotics for off-label indications in adults; and FDA actions.
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While a number of antiretroviral agents have been implicated in contributing to both insulin resistance and lipid abnormalities, HIV also directly causes metabolic disturbances.
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A double-blind, randomized, controlled trial conducted by the International Neonatal Immunotherapy Study (INIS) compared adjunctive therapy of human nonspecific polyvalent IgG intravenous immune globulin to placebo in the treatment of newborn infants with suspected or proven sepsis who were also receiving antibiotic therapy.
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Baseline production of PSMa subtypes was examined in 50 PVL-positive methicillin-susceptible Staphylococcus aureus (MSSA) and MRSA clinical isolates using liquid chromatography-tandem mass spectrometry (LC-MS-MS), and these results were compared to a control strain, LAC (USA300). MICs were determined using a broth macrodilution method.
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Outpatients with a diagnosis of either dentoalveolar or periodontal abscess or a diagnosis of gingival inflammatory infiltrates were randomized to receive either moxifloxacin 400 mg daily or clindamycin 300 mg QID, both for 5 days, in a prospective, randomized, placebo-controlled, double-dummy clinical trial design.
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A total of 783 children 6-24 months of age were followed for an entire respiratory season by four experienced otoscopists using pneumatic otoscopy of one ear, randomly selected for each child.
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In this issue: Apixaban could soon join the anticoagulation market; Chinese herbs for flu; chronic medication and discontinuation after hospitalization; and FDA actions.
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Malaria continues to be a global scourge, causing more than 200 million annual symptomatic cases and nearly a million annual deaths worldwide.
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A retrospective review of pediatric malaria at a Washington, DC, children's hospital identified 98 cases over 8 years from 1999 to 2006. Their mean age was 9.6 years. Approximately half of the children were long-term U.S. residents who had visited friends or relatives in their country of origin, and most of the others were recent immigrants.
