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Sanofi Pasteur announced September 28, 2012 a recall of 6 lots of Typhim Vi polysaccharide vaccine, the injectable "killed" vaccine. A significant portion of the stock has been shown to be insufficiently immunogenic and at risk for "low antigen content."
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An investigation initiated after a clinician reported to the Tennessee Department of Health on September 18, 2012 the case of a patient who developed meningitis due to Aspergillus fumigatus after having received an epidural corticosteroid injection at an ambulatory surgical center quickly identified a number of other suspect cases.
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At Duke University Health System, a tertiary-care medical center that has traditionally provided aggregated antimicrobial susceptibility data from both adult and pediatric isolates, antibiograms for Escherichia coli isolates from children ¡Ü12 years of age from July 2009 to September 2010 were developed and compared with antibiograms that combined adult and pediatric data. A total of 375 pediatric isolates were obtained from 327 patients.
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From November 2003 to November 2005, 254 cases of childhood diarrhea and 452 age- and geographically-matched (by zip code) controls were enrolled in a case-control study of the etiology of acute diarrhea among children 10-49 months of age presenting to a pediatric emergency department.
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Two men (one age 57 with no prior significant illnesses and one age 67 with type 2 diabetes) from northwestern Missouri presented separately to a hospital with illnesses characterized by fever, fatigue, diarrhea, thrombocytopenia and leukopenia. Hepatic transaminase levels subsequently became elevated in both patients, peaking between 8 and 10 days.
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Three HIV-infected patients with refractory, corticosteroid-dependent and life-threatening IRIS were presented.
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In this issue: Side effects of statins; effects of cannabis use; antihypertensives and lip cancer; and FDA actions.
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Clostridium difficile infection (CDI) is a major complication associated with antibiotic usage, and its incidence continues to increase. Management of CDI remains challenging despite new therapies and many patients suffer from recurrences. Interventions to limit acquisition of the disease are therefore urgently needed.
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Travel to the Middle East may have gotten less popular recently, but for those planning to travel for the annual pilgrimage to Makkah (Mecca) October 24-29, 2012, The National Travel Health Network has issued updated guidelines, as follows:
