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Macrophage Apoptosis by Anthrax Lethal Factor Through p38 MAP Kinase Inhibition

The bacterium Bacillus anthracis causes the death of macrophages, which may allow it to avoid detection by the innate immune system.

Treating Latent Tuberculosis Infection

Latent tuberculosis infection (LTBI) is a common reason for referral to infectious disease specialists. For the past few decades the standard therapy in the United States has been isoniazid for 9 months.

ID Grand Rounds — Stanford: Female, 52, with Fever and Progressive Weakness

A 52-year-old woman with no significant past medical history presented to Stanford Hospital in July, 2014, with fever and progressive weakness. She had been in her usual state of health until the day prior to admission, when she began to feel fatigued with subjective fevers and “restless legs.”

Dalbavancin — Formulary Considerations

Dalbavancin is a lipoglycopeptide antibiotic for intravenous administration with activity against Gram-positive organisms, including methicillin resistant Staphylococcus aureus that is distinguished by its extraordinarily long serum half-life that allows once weekly dosing.

Broad Spectrum Antibiotic Use in Infancy Sets Table for Early Childhood Obesity

From 2001 to 2013, Bailey and colleagues studied 65,480 children in a primary care network affiliated with Children’s Hospital of Pennsylvania that covered urban and suburban parts of Pennsylvania, New Jersey, and Delaware.