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In a shocking series of findings, this well-done prospective study showed that in men older than age 55 years a higher proportion of serum omega-3 fatty acids, specifically DHA, actually may increase the risk for high-grade prostate cancer.
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The study authors reviewed observational data on chocolate consumption and the risk of cardiometabolic disease, and found strong evidence of a protective effect. The wide variety of methods employed across studies, among other issues, make cause and effect assumptions premature, though they do fall in line with previous data suggesting chocolate's health benefits.
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In a prospective study of women with breast cancer who had undergone axillary node dissection, use of manual lymphatic drainage techniques over 5 months provided no additional preventive benefit with respect to development of arm lymphedema over general preventive lifestyle measures and individualized exercise therapy.
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This blinded, randomized, controlled trial found that a biofield therapy and a mock treatment did not differ in their effectiveness in relieving cancer-related fatigue, although they both were significantly better than control. The biofield therapy did lead to significantly greater cortisol variability, which is associated with fatigue.
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Atrial fibrillation (AF) is an irregular, disorganized, electrical activity of the atria.1 It is characterized by uncoordinated atrial activity that leads to inefficient atrial contraction and impaired ventricular filling, which leads to hemodynamic and mechanical functional impairments.
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Interpret the 12-lead ECG shown above obtained from a hemodynamically stable patient with underlying heart disease and new-onset palpitations. Despite the apparent QRS widening is this sinus tachycardia (arrow pointing to 'P waves' in lead II)?
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An ultra long-acting, orally-inhaled beta2-adrenergic agonist (LABA) has been approved for the treatment of chronic obstructive pulmonary disease (COPD). Indacaterol is formulated as a dry powder and is the first beta2-agonist to be dosed once-daily. It is marketed by Novartis as Arcapta™.
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Duplex ultrasonography should be used in asymptomatic patients with known or suspected carotid arterial stenosis and should be considered for use in asymptomatic patients who have symptomatic peripheral arterial disease, coronary artery disease, or an atherosclerotic aortic aneurysm, and even in the asymptomatic patients who simply are at high cardiovascular risk.
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Sleep-disordered breathing is a significant risk factor for cognitive decline and continuous positive airway pressure (CPAP) therapy may prevent or slow this process.
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The authors conclude that in a population-based cohort undergoing 4 years of follow-up, the prevalence of diastolic dysfunction increased and that diastolic dysfunction was associated with development of heart failure during 6 years of subsequent follow-up.
