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Historically, men with high-risk prostate cancer were believed to have low survival rates after definitive treatment with either surgery or radiation. However, long-term results of dose-escalated radiotherapy of doses ≥ 75.6 Gy, along with long-term androgen deprivation therapy (ADT), demonstrate 5-year survival rate of 92%, 5-year biochemical control rate of 82%, and symptomatic local failure rate of 0%. Death from prostate cancer was only 5.5% at 10 years in men treated with high-dose radiation therapy and ADT.
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In a study of men in the Veterans Affairs health care system with low serum testosterone levels, the use of testosterone therapy was associated with an increased risk of mortality, myocardial infarction, or ischemic stroke.
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The use of dabigatran in patients with mechanical heart valves compared with patients receiving warfarin was associated with increased rates of thromboembolic and bleeding complications, thus demonstrating no benefit and an excess risk.
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RSV occurs primarily in the winter months in the United States and is a cause of significant morbidity and mortality, particularly in the very young and very old.
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Those receiving spiritual support from medical personnel rather than community-based religious organizations were more likely to receive hospice care at the end of life.
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Supplementing patients with Parkinson's disease with 1200 IU of vitamin D3 may stabilize Parkinson's disease symptoms in patients with vitamin D receptor CT and TT genotypes but not the FokI CC genotype.
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This prospective trial performed at an infertility clinic in Brazil randomized 84 women who had at least two prior failed in vitro fertilization (IVF) attempts to three groups. The first group had acupuncture plus moxibustion in addition to IVF, the second had sham acupuncture and IVF, and the third group only underwent IVF.
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The long-awaited JNC-7 report was recently published in summary form; a more comprehensive manuscript will be forthcoming. JNC-7 takes into account many of the randomized controlled trials dealing with hypertension published over the past few years, and thus, is very much up to date. Some highlights of the report are as follows.
