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Special Subgroups in Hypertension: Obese Hypertensives; Selection Criteria for Lung Cancer Screening; Extended Treatment of VTE with Dabigatran vs Warfarin
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Borderline personality disorder (BPD) is a striking personality dysfunction characterized by inherent difficulties with self-regulation as well as chronic self-destructive behavior. In patients with this disorder, the pain experience is seemingly paradoxical. During acute self-destructive acts, up to 80% of individuals with BPD describe attenuated responses to pain (i.e., high tolerance of pain).
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Gabapentin for Chronic Cough; Can Statins Reduce Cancer-Related Mortality?; Are All of Those Multivitamin Dollars Well Spent?
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The FDA has approved the first in class α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor antagonist for the treatment of seizures. Perampanel is an orally active noncompetitive AMPA antagonist. The drug is marketed by Eisai Inc. as Fycompa.
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The ECG shown above was obtained from a 74-year-old woman who presented with abrupt onset of severe renal colic but no chest pain.
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Menopausal hormone therapy and risk of VTE and AD; patients' understanding of chemotherapy benefits; and FDA actions.
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In the JUPITER primary prevention trial, the cardiovascular and mortality benefits of statin therapy exceeded the diabetes hazard, including patients at high risk of developing diabetes.
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The authors conducted a literature review of Medline and the Cochrane database to identify studies comparing outcomes in Bells palsy patients who received steroid/antiviral agents vs no medication. Patients with new onset Bells palsy treated with steroids displayed significantly better improvement in facial function compared with patients not taking this medication.
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Dabigatran has been demonstrated to decrease the rate of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (AF) by one-third, while also decreasing the rate of intracranial bleeding by two-thirds compared with warfarin.
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