Special Subgroups in Hypertension: Obese Hypertensives; Selection Criteria for Lung Cancer Screening; Extended Treatment of VTE with Dabigatran vs Warfarin
Borderline personality disorder (BPD) is a striking personality dysfunction characterized by inherent difficulties with self-regulation as well as chronic self-destructive behavior. In patients with this disorder, the pain experience is seemingly paradoxical. During acute self-destructive acts, up to 80% of individuals with BPD describe attenuated responses to pain (i.e., high tolerance of pain).
Gabapentin for Chronic Cough; Can Statins Reduce Cancer-Related Mortality?; Are All of Those Multivitamin Dollars Well Spent?
The FDA has approved the first in class α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptor antagonist for the treatment of seizures. Perampanel is an orally active noncompetitive AMPA antagonist. The drug is marketed by Eisai Inc. as Fycompa.
The ECG shown above was obtained from a 74-year-old woman who presented with abrupt onset of severe renal colic but no chest pain.
Menopausal hormone therapy and risk of VTE and AD; patients' understanding of chemotherapy benefits; and FDA actions.
In the JUPITER primary prevention trial, the cardiovascular and mortality benefits of statin therapy exceeded the diabetes hazard, including patients at high risk of developing diabetes.
The authors conducted a literature review of Medline and the Cochrane database to identify studies comparing outcomes in Bells palsy patients who received steroid/antiviral agents vs no medication. Patients with new onset Bells palsy treated with steroids displayed significantly better improvement in facial function compared with patients not taking this medication.
Dabigatran has been demonstrated to decrease the rate of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (AF) by one-third, while also decreasing the rate of intracranial bleeding by two-thirds compared with warfarin.