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Attenuated CV Benefits of Clopidogrel in Diabetes; Is A1c Always the Best Game in Town to Monitor Type 2 Diabetes?
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The 12-lead ECG shown above was obtained from a patient with new-onset chest pain. Where is the acute lesion likely to be?
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More than half of patients undergoing non-cardiac surgery and polysomnography had obstructive sleep apnea, which was associated with an increased risk of perioperative complications, including hypoxemia, ICU transfer, and prolonged length of stay.
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There do not appear to be any safety issues with the long-term use of statins.
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The FDA has approved a once-weekly treatment for type 2 diabetes. The new product is a subcutaneously administered extended-release form of the glucagon-like peptide-1 receptor agonist, exenatide. Exenatide extended-release is marketed by Amylin Pharmaceuticals and Alkermes PLC as Bydureon.
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Zinc deficiency is defined as a serum zinc level < 60 mg/dL. Unfortunately, there is some question about the reliability of zinc levels to accurately reflect zinc status, since some persons with prototypic symptoms of zinc deficiency (loss of appetite, diarrhea, hair loss, delayed wound healing, and smell and taste disturbances) have normal zinc levels.
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Aspirin can reduce the risk of nonfatal myocardial infarction, but not mortality, in people without coronary vascular disease, at the expense of increased risk of bleeding. It should not be routinely recommended.
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In November 2011, the Centers for Disease Control and Prevention presented data on emergency hospitalizations because of adverse drug reactions. The report showed that insulin and oral hypoglycemic agents caused nearly 25% of the medication-induced hospitalizations in older adults in the United States.
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When routinely cultured, essentially all ICU privacy curtains were found to be contaminated with potential pathogens at least some of the time. Recovered organisms included methicillin-resistant staphylococci and vancomycin-resistant enterococci.
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In this study population with a 2% average risk of a major coronary event per year, LDL cholesterol, apolipoproteins, and LDL particle concentrations had similar and strong associations for major vascular events. The independent predictive value of HDL measures is less clear.
