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Among patients with coronary heart disease and LDL-cholesterol levels less than 70 mg/dL, there is no incremental clinical benefit from the addition of niacin to statin therapy during a 36-month follow-up, despite improvements in HDL-cholesterol and triglyceride levels.
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Aspirin can reduce the risk of nonfatal myocardial infarction, but not mortality, in people without coronary vascular disease, at the expense of increased risk of bleeding. It should not be routinely recommended.
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Results from this small, 8-week crossover study suggest that the antioxidant Pycnogenol, which also possesses anti-inflammatory actions, could help improve endothelial function in people with stable coronary artery disease.
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L-carnitine is both an amino acid and a conditionally essential nutrient, defined as an organic compound which is usually produced in sufficient quantities by the body.
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Both vitamin D deficiency and supplementation with vitamin D are significantly associated with several cardiovascular outcomes, including mortality.
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The first results of a 5-year study of the effects a mindfulness-based stress reduction program on medical complications and psychosocial outcomes in patients with type 2 diabetes show prolonged reduction in psychological distress and depression compared to usual care.
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The FDA has approved a second oral drug for the treatment of multiple sclerosis (MS). Teriflunomide, a metabolite of leflunomide and a pyrimidine synthesis inhibitor, is an immunomodulatory agent. It is marketed by Sanofi Aventis as Aubagio.
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Several commonly used photosensitizing antihypertensive drugs can confer as much as a four-fold increase in the risk of lip cancer when prescribed long-term in non-Hispanic whites.
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This paper updates the American Headache Society and American Academy of Neurology guidelines for prevention of episodic migraine that were previously published in 2000.
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Results of this year-long intervention trial suggest that an ethanolic extract of curcumin could, together with appropriate dietary and lifestyle changes, play a role in slowing the progression from prediabetes to type 2 diabetes.